Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.53 |
| ▸ | ALPL | P05186 | 4/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373726 | 0.93 | AR (0.61) | ARALPLGRIA2GRIA4CA9 | |
| SCHEMBL14348166 | 0.85 | AR (0.50) | ARCHEK1CCNCCDK8 | |
| SCHEMBL5359879 | 0.81 | AR (0.52) | ARALPLFNTAFNTB | |
| SCHEMBL5362087 | 0.77 | AR (0.60) | ARGRIA2GRIA4CHEK1CCNC | |
| SCHEMBL5359277 | 0.75 | AR (0.61) | ARGRIA2GRIA4CHEK1CCNC | |
| SCHEMBL5361524 | 0.72 | AR (0.54) | ARCHEK1CCNCCDK8 | |
| SCHEMBL5362232 | 0.71 | AR (0.61) | ARGRIA2GRIA4CCNCCDK8 | |
| SCHEMBL5362254 | 0.71 | AR (0.60) | ARGRIA2GRIA4FNTAFNTB | |
| SCHEMBL14348310 | 0.70 | AR (0.53) | ARGRIA2GRIA4CHEK1CCNC | |
| SCHEMBL6468062 | 0.69 | AR (1.00) | ARGRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |