Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004189 | 0.79 | APP (0.54) | L3MBTL1APPOPRD1OPRK1OPRM1 | |
| SCHEMBL415372 | 0.74 | CYP3A4 (0.56) | KMT2AMEN1OPRM1ALDH1A1 | |
| SCHEMBL27685983 | 0.70 | CA12 (0.53) | LMNAKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL17177194 | 0.70 | TSHR (0.48) | LMNAKMT2AMEN1L3MBTL1APP | |
| SCHEMBL13689912 | 0.69 | MEN1 (0.56) | KMT2AMEN1L3MBTL1RORCOPRD1 | |
| SCHEMBL8824371 | 0.69 | OPRD1 (0.54) | LMNAL3MBTL1APPOPRD1OPRK1 | |
| SCHEMBL10237611 | 0.69 | RORC (0.44) | KMT2AMEN1RORCOPRD1OPRK1 | |
| SCHEMBL2675366 | 0.69 | RORC (0.44) | KMT2AMEN1RORCOPRD1OPRK1 | |
| SCHEMBL17707495 | 0.68 | OPRM1 (0.47) | KMT2AMEN1OPRM1ALDH1A1 | |
| SCHEMBL27623362 | 0.68 | CA12 (0.50) | LMNAKMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |