Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435318 | 0.77 | CYP1B1 (0.54) | MAPTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL1397634 | 0.73 | NPC1 (0.46) | MAPTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL1435403 | 0.72 | CYP1B1 (0.54) | MAPTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL1435433 | 0.72 | TP53 (0.53) | MAPTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL1435687 | 0.72 | MAPT (0.60) | MAPTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL1435404 | 0.72 | MAPT (0.56) | MAPTKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1435414 | 0.72 | MAOB (0.56) | MAPTKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18407351 | 0.71 | RAB9A (0.64) | MAPTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL1435357 | 0.71 | HTR2C (0.52) | MAPTKMT2ALMNARAB9ATNFRSF1A | |
| SCHEMBL15525567 | 0.69 | KMT2A (0.58) | MAPTKMT2ALMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | claimed |
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | disclosed |