SCHEMBL14352897

SCHEMBL14352897

CCCCC(F)(F)C(O)CC[C@H]1[C@H](OC2CCCCO2)CC(O)[C@@H]1CCCCCCC(=O)OCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PTGFR P43088 15/20 0.38
▸ PTGER1 P34995 9/20 0.38
▸ PTGER2 P43116 2/20 0.38
▸ PTGER3 P43115 2/20 0.35
▸ TBXA2R P21731 2/20 0.35
▸ PTGDR Q13258 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11912319 1.00 PTGFR (0.38) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL3009599 1.00 PTGFR (0.38) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL3009597 1.00 PTGFR (0.38) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL14352819 0.90 PTGFR (0.37) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL14352820 0.90 PTGFR (0.37) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL15106761 0.90 PTGFR (0.44) PTGFRPTGER3TBXA2RMEN1ALDH1A1
SCHEMBL15106763 0.90 PTGFR (0.44) PTGFRPTGER3TBXA2RMEN1ALDH1A1
SCHEMBL8633845 0.90 PTGFR (0.37) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL8414060 0.90 PTGFR (0.37) PTGFRPTGER1PTGER2PTGER3TBXA2R
SCHEMBL11916721 0.89 MEN1 (0.34) PTGER2MEN1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2726472-B1 METHOD FOR PREPARING A FATTY ACID DERIVATIVE R-TECH UENO LTD (JP) 2016-12-21 — — EP disclosed
US-9242950-B2 Method for preparing a fatty acid derivative R-TECH UENO, LTD. (JP) 2016-01-26 — — US disclosed
US-20130005995-A1 METHOD FOR PREPARING A FATTY ACID DERIVATIVE SUCAMPO AG (CH) 2013-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130005995-A1 METHOD FOR PREPARING A FATTY ACID DERIVATIVE ALOX12, ELOVL1, ALOX5 PTGFR 2590/4885PTGER1 276/4885PTGER2 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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