Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.71 |
| ▸ | HTR1A | P08908 | 3/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487380 | 0.91 | CYP2D6 (0.59) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL8967625 | 0.90 | CHRM2 (0.72) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL11489480 | 0.89 | CYP2D6 (0.56) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL11495711 | 0.87 | ALDH1A1 (0.55) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL11487164 | 0.87 | ALDH1A1 (0.55) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL11489338 | 0.85 | LTA4H (0.55) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL14354524 | 0.83 | CHRM2 (0.56) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| Pridinol SCHEMBL143298 | 0.83 | CHRM2 (1.00) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| SCHEMBL11492973 | 0.82 | KCNH2 (0.61) | CYP2D6CHRM2CHRM1KCNH2HTR1A | |
| Pridinol SCHEMBL363996 | 0.81 | CHRM2 (0.97) | CYP2D6CHRM2CHRM1KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957081-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2015-02-17 | — | — | US | claimed |
| US-20130005748-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2013-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005748-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | ZAP70, IGF1R, PTK2 | CYP2D6 4747/4885CHRM2 3610/4885CHRM1 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.