Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.72 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.72 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.72 |
| ▸ | HTR1A | P08908 | 3/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 1/20 | 0.72 |
| ▸ | DRD1 | P21728 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | DRD3 | P35462 | 1/20 | 0.72 |
| ▸ | SCN1A | P35498 | 1/20 | 0.72 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.72 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492973 | 0.91 | KCNH2 (0.61) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL14354382 | 0.90 | CYP2D6 (0.71) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Diphenidol SCHEMBL34469 | 0.84 | CHRM3 (1.00) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Diphenidol SCHEMBL195192 | 0.83 | CHRM3 (1.00) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL10307554 | 0.82 | CHRM3 (0.97) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL11487380 | 0.82 | CYP2D6 (0.59) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL11489162 | 0.81 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL11496128 | 0.81 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL11489416 | 0.81 | CHRM2 (0.49) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Diphenidol SCHEMBL15531902 | 0.81 | CHRM3 (0.94) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |