SCHEMBL14354597

SCHEMBL14354597

O=S(=O)(c1cccc(S(=O)(=O)C(Cl)(Cl)Cl)n1)C(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LOX P28300 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14354612 0.78 LOX (0.31) LOX
SCHEMBL3983033 0.76 KDM4E (0.50) TSHRALDH1A1HSD17B10TDP1LOX
SCHEMBL14340562 0.76 PKM (0.43) TSHRALDH1A1HSD17B10
SCHEMBL9626210 0.75 PNMT (0.31)
SCHEMBL14340561 0.75
SCHEMBL14354595 0.74 PNMT (0.35)
SCHEMBL7603249 0.72 ALDH1A1 (0.55) CYP3A4TSHRALDH1A1HSD17B10TDP1
SCHEMBL5547208 0.67 LOX (0.51) ALDH1A1LOX
SCHEMBL8847325 0.67 TSHR (0.42) TSHRALDH1A1HSD17B10TDP1LOX
SCHEMBL9626752 0.67 ALDH1A1 (0.36) ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070281246-A1 Processing method of light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-06 US disclosed
US-7220530-B2 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-22 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7169535-B2 Photosensitive composition and photosensitive lithographic printing plate KONICA MINOLTA HOLDINGS, INC. (JP) 2007-01-30 US disclosed