Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435550 | 0.88 | CYP1B1 (0.57) | MAPTMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL7444589 | 0.79 | CSNK2A1 (0.59) | MAPTMAOBCSNK2A1MEN1KMT2A | |
| SCHEMBL7431073 | 0.77 | CSNK2A1 (0.57) | MAPTMAOBCSNK2A1MEN1KMT2A | |
| SCHEMBL22352682 | 0.76 | MAOA (0.58) | MAPTMAOBCSNK2A1MEN1KMT2A | |
| SCHEMBL1435403 | 0.76 | CYP1B1 (0.54) | MAPTMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL1435687 | 0.76 | MAPT (0.60) | MAPTMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL1435433 | 0.76 | TP53 (0.53) | MAPTMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL4098407 | 0.74 | MEN1 (0.68) | MAPTMAOBCSNK2A1MEN1KMT2A | |
| SCHEMBL4098410 | 0.74 | MEN1 (0.68) | MAPTMAOBCSNK2A1MEN1KMT2A | |
| SCHEMBL7431076 | 0.74 | CSNK2A1 (0.56) | MAPTMAOBCSNK2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | claimed |
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | disclosed |