Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160338 | 0.82 | POLB (0.48) | CYP11B1CYP11B2ALDH1A1CYP3A4POLB | |
| SCHEMBL17366415 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLB | |
| SCHEMBL29574715 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLB | |
| SCHEMBL5144124 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2GRM5IDO1ALDH1A1 | |
| SCHEMBL23110060 | 0.79 | KMT2A (0.50) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL13536764 | 0.79 | CYP11B1 (0.51) | CYP11B1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL13221922 | 0.75 | KIF11 (0.39) | ALDH1A1LMNAMAPTNPC1CYP1A2 | |
| SCHEMBL550506 | 0.74 | MAPT (0.55) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL16290260 | 0.74 | MAPT (0.55) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL20357269 | 0.74 | CYP11B1 (0.48) | CYP11B1CYP11B2GRM5IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |