Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30747787 | 0.86 | CYP11B1 (0.56) | CYP11B1KDM4ECYP2A6ALDH1A1L3MBTL1 | |
| SCHEMBL28682644 | 0.86 | CYP11B1 (0.56) | CYP11B1KDM4ECYP2A6ALDH1A1L3MBTL1 | |
| SCHEMBL30382878 | 0.82 | LDHA (0.52) | CYP11B1CYP11B2MAPTCYP3A4CYP2A6 | |
| SCHEMBL2718039 | 0.82 | LDHA (0.52) | CYP11B1CYP11B2MAPTCYP3A4CYP2A6 | |
| SCHEMBL1356310 | 0.81 | ALDH1A1 (0.44) | CYP11B1KDM4ELMNACYP2A6ALDH1A1 | |
| SCHEMBL14355115 | 0.81 | CYP11B1 (0.45) | CYP11B1CYP11B2GRM5WNT3AIDO1 | |
| SCHEMBL5572542 | 0.81 | CYP11B1 (0.46) | CYP11B1CYP11B2KDM4ECYP3A4CYP2A6 | |
| SCHEMBL4417307 | 0.79 | HSD17B10 (0.54) | CYP11B1KDM4EMAPTALDH1A1MITF | |
| SCHEMBL13527931 | 0.79 | CYP11B1 (0.48) | CYP11B1CYP11B2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13568531 | 0.79 | ALDH5A1 (0.54) | CYP11B1KDM4EMAPTALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20050085642-A1 | Novel bipyridine derivatives | SANKIO CHEMICAL CO., LTD. | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085642-A1 | Novel bipyridine derivatives | PFAS, CBR3, Q6ZSR9 | CYP11B1 2629/4885CYP11B2 2638/4885GRM5 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.