Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871770 | 0.80 | EPHX1 (0.41) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL187942 | 0.80 | EPHX1 (0.41) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL3871772 | 0.80 | EPHX1 (0.41) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL27431107 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL14130850 | 0.77 | AKR1C3 (0.48) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL15052966 | 0.77 | AKR1C3 (0.48) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL15969887 | 0.77 | AKR1C3 (0.48) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL7446722 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL28850187 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL367455 | 0.73 | AKR1C3 (0.59) | ALDH1A1TSHRKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301027-B2 | Process for the preparation of Imiquimod and intermediates thereof | DIPHARMA S.P.A. (IT) | 2007-11-27 | — | — | US | disclosed |