SCHEMBL367455

SCHEMBL367455

CC(=Cc1ccccc1C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.59
APEX1 P27695 9/20 0.49
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
KDM4E B2RXH2 2/20 0.43
GMNN O75496 1/20 0.43
LMNA P02545 1/20 0.43
PMP22 Q01453 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTT P42858 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
NR4A2 P43354 1/20 0.41
RXRG P48443 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3736899 1.00 AKR1C3 (0.59) AKR1C3APEX1ALDH1A1TSHRKDM4E
SCHEMBL7134074 0.88 AKR1C3 (0.47) AKR1C3APEX1ALDH1A1TSHRKDM4E
SCHEMBL31666241 0.87 AKR1C3 (0.68) AKR1C3APEX1KDM4ELMNAHTT
SCHEMBL3893886 0.87 AKR1C3 (0.68) AKR1C3APEX1KDM4ELMNAHTT
SCHEMBL8746671 0.87 AKR1C3 (0.68) AKR1C3APEX1KDM4ELMNAHTT
SCHEMBL2439822 0.86 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRKDM4EGMNN
SCHEMBL17122439 0.86 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRKDM4EGMNN
SCHEMBL2439824 0.86 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRKDM4EGMNN
SCHEMBL13287298 0.86 ALDH1A1 (0.50) AKR1C3ALDH1A1TSHRKDM4EGMNN
SCHEMBL22042820 0.85 AKR1C3 (0.52) AKR1C3APEX1ALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458082-B1 Encapsulated toner compositions XEROX CORP (US) 1996-09-04 EP claimed
US-11896593-B2 Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder BIO-PHARM SOLUTIONS CO., LTD. (KR) 2024-02-13 US disclosed
US-11795151-B2 Benzotriazole compound MIYOSHI OIL & FAT CO., LTD. (JP) 2023-10-24 US disclosed
EP-4211125-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING A PSYCHIATRIC DISORDER Bio-Pharm Solutions Co., Ltd. (KR) 2023-07-19 EP disclosed
US-20220218702-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING A PSYCHIATRIC DISORDER BIO-PHARM SOLUTIONS CO., LTD. (KR) 2022-07-14 US disclosed
EP-2574976-B1 Ophthalmic devices having a highly selective violet light transmissive filter JOHNSON & JOHNSON SURGICAL VISION INC (US) 2021-08-11 EP disclosed
US-20200325107-A1 BENZOTRIAZOLE COMPOUND MIYOSHI OIL & FAT CO., LTD. (JP) 2020-10-15 US disclosed
US-10481314-B2 Display apparatus and polarizer thereof LG DISPLAY CO., LTD. (KR) 2019-11-19 US disclosed
EP-3517571-A1 (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, MOLDED BODY OF SAME, AND METHOD FOR PRODUCING MOLDED BODY Mitsubishi Gas Chemical Company, Inc. (JP) 2019-07-31 EP disclosed
EP-3443959-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN Bio-Pharm Solutions Co., Ltd. (KR) 2019-02-20 EP disclosed
WO-2004015020-A1 ADHESIVE MATERIALS HAVING A HIGH REFRACTIVE INDEX BASED ON ACRYLATE BLOCK COPOLYMERS TESA AG (DE) 2004-02-19 WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5821306-A POLYMER BLEND CONSISTING OF POLYPHENYLETHYL METHACRYLATE AND POLYPHENYLETHYL ACRYLATE PHARMACIA & UPJOHN GRONINGEN BV (NL) 1998-10-13 US disclosed
US-5691094-A LITHOGRAPHY, INPROVED TRANSFERABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-11-25 US disclosed
EP-0784652-A1 INTRAOCULAR LENS MATERIALS Pharmacia & Upjohn Aktiebolag (SE) 1997-07-23 EP disclosed
US-5648191-A Method for preparation of printing plate by electrophotographic process FUJI PHOTO FILM CO., LTD. (JP) 1997-07-15 US disclosed
US-5597672-A Method for preparation of printing plate by electrophotographic process FUJI PHOTO FILM CO., LTD. (JP) 1997-01-28 US disclosed
WO-1996011235-A1 INTRAOCULAR LENS MATERIALS PHARMACIA & UPJOHN AB (SE) 1996-04-18 WO disclosed
US-5501929-A TONER IMAGES ON TRANSFER LAYER OF THERMOPLASTIC RESIN FORLIGHT SENSITIVE ELEMENT FUJI PHOTO FILM CO., LTD. (JP) 1996-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220218702-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING A PSYCHIATRIC DISORDER SLC6A4, SLC6A3, SLC6A2 AKR1C3 4119/4885APEX1 3885/4885ALDH1A1 776/4885
US-11795151-B2 Benzotriazole compound PRXL2A, HAX1, XRN2 AKR1C3 4016/4885APEX1 2120/4885ALDH1A1 2237/4885
US-11896593-B2 Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder SLC6A4, SLC6A3, SLC6A2 AKR1C3 4119/4885APEX1 3885/4885ALDH1A1 776/4885
US-20200325107-A1 BENZOTRIAZOLE COMPOUND PRXL2A, HAX1, XRN2 AKR1C3 4016/4885APEX1 2120/4885ALDH1A1 2237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.