Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | DRD2 | P14416 | 5/20 | 0.63 |
| ▸ | DRD3 | P35462 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399496 | 0.94 | KDM4E (0.75) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL21486448 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL2781997 | 0.84 | DRD2 (0.68) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL2781729 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL1869179 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL30839768 | 0.81 | ALDH1A1 (0.73) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL25003289 | 0.81 | ALDH1A1 (0.73) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL10934231 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL11613977 | 0.81 | ADRA2C (0.62) | KDM4EALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL2783736 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1L3MBTL1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |