Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.48 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355761 | 0.86 | SETDB1 (0.56) | BRD9BRPF1NCF1BRD4LIPG | |
| SCHEMBL14355994 | 0.85 | BRD9 (0.48) | BRD9LIPGDRD2HTR2CL3MBTL1 | |
| SCHEMBL5340539 | 0.81 | GPR119 (0.49) | KDM4EGAAHTTALDH1A1 | |
| SCHEMBL14355870 | 0.80 | NCF1 (0.57) | BRD9BRPF1NCF1BRD4LIPG | |
| SCHEMBL7294686 | 0.78 | NPBWR1 (0.52) | KDM4EDRD2HTR2CL3MBTL1HTR1A | |
| SCHEMBL1487941 | 0.77 | NCF1 (0.58) | BRD9BRPF1NCF1BRD4BRD7 | |
| SCHEMBL414567 | 0.77 | NCF1 (0.58) | BRD9BRPF1NCF1BRD4BRD7 | |
| SCHEMBL14355832 | 0.77 | HSD17B10 (0.71) | KDM4EHSD17B10POLBMAPK1CASP1 | |
| SCHEMBL19421312 | 0.77 | HTR7 (0.48) | NCF1DRD2HTR1AFABP3FABP4 | |
| SCHEMBL19421293 | 0.77 | HTR7 (0.46) | NCF1HTR2CHTR1AHTR2AFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |