Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944138 | 0.85 | ALDH1A1 (0.60) | POLBMEN1KMT2AMAPK10NPSR1 | |
| SCHEMBL6991512 | 0.85 | CHEK1 (0.49) | MAPK1MEN1KMT2AGAANPSR1 | |
| SCHEMBL8716632 | 0.84 | KMT2A (0.46) | MAPK1POLBMEN1KMT2AGAA | |
| SCHEMBL8716846 | 0.84 | WDR5 (0.48) | MAPK1MEN1KMT2AGAANPSR1 | |
| SCHEMBL8716619 | 0.82 | WDR5 (0.51) | MEN1KMT2AGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL2830700 | 0.81 | F10 (0.64) | MAPK1POLBSMN1; SMN2NPC1 | |
| SCHEMBL13159555 | 0.81 | MAPK1 (0.64) | MAPK1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL8711040 | 0.81 | WDR5 (0.54) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8711310 | 0.81 | MAPK8 (0.56) | MAPK1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL5172621 | 0.79 | KDM4E (0.45) | HSD17B10GAAALDH1A1KDM4EMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |