Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 9/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391141 | 1.00 | CCR5 (0.41) | CCR5AKR1C3MGLLMAPTCHRNA7 | |
| SCHEMBL14356018 | 0.85 | MGLL (0.52) | MGLL | |
| SCHEMBL13391712 | 0.85 | MGLL (0.52) | MGLL | |
| SCHEMBL13391090 | 0.83 | LSS (0.50) | AKR1C3 | |
| SCHEMBL13391256 | 0.79 | CCR5 (0.38) | CCR5 | |
| SCHEMBL12893655 | 0.76 | MGLL (0.49) | CCR5MGLLMAPT | |
| SCHEMBL13391351 | 0.75 | TACR3 (0.47) | — | |
| SCHEMBL14355764 | 0.75 | CYP3A4 (0.54) | MAPT | |
| SCHEMBL13391433 | 0.75 | CYP3A4 (0.54) | MAPT | |
| SCHEMBL13391460 | 0.75 | CYP3A4 (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |