Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391712 | 1.00 | MGLL (0.52) | MGLLMEN1KMT2AHSD11B1KDM4E | |
| SCHEMBL13391737 | 0.89 | MGLL (0.52) | MGLLMEN1KMT2AHSD11B1KDM4E | |
| SCHEMBL14356016 | 0.89 | MGLL (0.52) | MGLLMEN1KMT2AHSD11B1KDM4E | |
| SCHEMBL13391141 | 0.85 | CCR5 (0.41) | MGLL | |
| SCHEMBL14355891 | 0.85 | CCR5 (0.41) | MGLL | |
| SCHEMBL13391092 | 0.79 | LSS (0.58) | MGLLMEN1KMT2AHSD11B1 | |
| SCHEMBL8105641 | 0.78 | CYP3A4 (0.49) | MGLLMEN1KMT2A | |
| SCHEMBL28975833 | 0.77 | POLB (0.68) | MGLLMEN1KMT2AHSD11B1KDM4E | |
| SCHEMBL9444391 | 0.74 | KCNH2 (0.49) | MGLLMEN1KMT2AKDM4EPOLB | |
| SCHEMBL14456962 | 0.73 | CNR1 (0.65) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |