Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 5/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | ABCC4 | O15439 | 4/20 | 0.80 |
| ▸ | ABCC2 | Q92887 | 4/20 | 0.80 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.80 |
| ▸ | GAA | P10253 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | ABCC3 | O15438 | 3/20 | 0.80 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.80 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.80 |
| ▸ | SLCO1A2 | P46721 | 2/20 | 0.80 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.80 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302850 | 1.00 | ABCB11 (0.80) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL30063061 | 1.00 | ABCB11 (0.80) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL29534651 | 1.00 | ABCB11 (0.80) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL14252218 | 0.94 | ABCB11 (0.79) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL23541658 | 0.93 | ABCB11 (0.83) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL23541652 | 0.93 | MAPT (0.83) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL23594215 | 0.93 | ABCB11 (0.83) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL29559659 | 0.93 | ABCB11 (0.83) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL23510705 | 0.93 | MAPT (0.83) | ABCB11MAPTABCC4ABCC2TBXA2R | |
| SCHEMBL31447566 | 0.93 | ABCB11 (0.83) | ABCB11MAPTABCC4ABCC2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300924-B2 | Anti-infective phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300924-B2 | Anti-infective phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2007-11-27 | — | — | US | disclosed |