SCHEMBL29534651

SCHEMBL29534651

CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(C=O)c(O)c4c3C2=O)NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB11 O95342 5/20 0.80
▸ MAPT P10636 4/20 0.80
▸ ABCC4 O15439 4/20 0.80
▸ ABCC2 Q92887 4/20 0.80
▸ TBXA2R P21731 3/20 0.80
▸ GAA P10253 3/20 0.80
▸ MAPK1 P28482 3/20 0.80
▸ ABCC3 O15438 3/20 0.80
▸ CHRM1 P11229 3/20 0.80
▸ NR1I2 O75469 3/20 0.80
▸ ALDH1A1 P00352 2/20 0.80
▸ SLCO2B1 O94956 2/20 0.80
▸ ADRA1A P35348 2/20 0.80
▸ SLCO1A2 P46721 2/20 0.80
▸ SLCO1B3 Q9NPD5 2/20 0.80
▸ SLCO1B1 Q9Y6L6 2/20 0.80
▸ KDM4E B2RXH2 2/20 0.80
▸ MEN1 O00255 2/20 0.80
▸ KMT2A Q03164 2/20 0.80
▸ TDP1 Q9NUW8 2/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13302850 1.00 ABCB11 (0.80) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL14356353 1.00 ABCB11 (0.80) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL30063061 1.00 ABCB11 (0.80) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL14252218 0.94 ABCB11 (0.79) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL23541658 0.93 ABCB11 (0.83) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL23541652 0.93 MAPT (0.83) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL23594215 0.93 ABCB11 (0.83) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL29559659 0.93 ABCB11 (0.83) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL23510705 0.93 MAPT (0.83) ABCB11MAPTABCC4ABCC2TBXA2R
SCHEMBL31447566 0.93 ABCB11 (0.83) ABCB11MAPTABCC4ABCC2TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102392-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR NEURODEGENERATIVE DISEASES MEDILABO RFP INC (JP) 2026-04-16 — — US claimed
US-12521387-B2 Prophylactic or therapeutic drug for neurodegenerative diseases MEDILABO RFP, INC. (JP) 2026-01-13 — — US claimed
US-20250120943-A1 RIFAMYCIN OPHTHALMIC COMPOSITION AND USE THEREOF AMD THERAPEUTICS LLC (US) 2025-04-17 — — US claimed
EP-4531844-A1 RIFAMYCIN OPHTHALMIC COMPOSITION AND USE THEREOF AMD Therapeutics LLC (US) 2025-04-09 — — EP claimed
CN-119300821-A Ophthalmic compositions of rifamycin and uses thereof AMD治疗有限责任公司 2025-01-10 — — CN claimed
WO-2023234423-A1 RIFAMYCIN OPHTHALMIC COMPOSITION AND USE THEREOF AMD THERAPEUTICS LLC (US) 2023-12-07 — — WO claimed
EP-3650024-B1 PHARMACEUTICAL COMPOSITION FOR NASAL ADMINISTRATION COMPRISING RIFAMPICINS FOR TREATING DEMENTIA MEDILABO RFP INC (JP) 2023-10-25 — — EP claimed
CN-113933399-B Method for separating and detecting rifampicin and related impurities in rifampicin for injection 重庆华邦制药有限公司 2023-08-15 — — CN claimed
CN-115656364-A Detection method of related substances in rifampicin and application of detection method in MNP (MNP) monitoring 中国食品药品检定研究院 2023-01-31 — — CN claimed
CN-122080018-A Synthetic process for preparing rifampicin by using rifamycin O as starting material — 2026-05-26 — — CN disclosed
EP-4736953-A2 THERAPEUTIC AGENTS AND METHODS Pop Test Oncology LLC (US) 2026-05-06 — — EP disclosed
US-20260102392-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR NEURODEGENERATIVE DISEASES MEDILABO RFP INC (JP) 2026-04-16 — — US disclosed
EP-3534910-B1 RIFAMPICIN DERIVATIVES WITH ANTIBACTERIAL ACTIVITY POP TEST ONCOLOGY LLC (US) 2026-03-25 — — EP disclosed
EP-4706655-A1 PREVENTIVE OR THERAPEUTIC AGENT FOR NEURODEGENERATIVE DISEASE Medilabo RFP, Inc. (JP) 2026-03-11 — — EP disclosed
US-11583494-B2 Pharmaceutical composition for nasal administration MEDILABO RFP, INC. (JP) 2023-02-21 — — US disclosed
CN-115656364-A Detection method of related substances in rifampicin and application of detection method in MNP (MNP) monitoring 中国食品药品检定研究院 2023-01-31 — — CN disclosed
WO-2023284777-A1 COPOLYMER FILM, ENZYME CATALYSIS SELF-ASSEMBLY SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 中国科学院天津工业生物技术研究所 2023-01-19 — — WO disclosed
US-20220298203-A1 THERAPEUTIC AGENTS AND METHODS POP TEST ONCOLOGY LLC 2022-09-22 — — US disclosed
US-11447502-B2 Antibacterial agents: dual-targeted RNA polymerase inhibitors RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-09-20 — — US disclosed
US-20220125782-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR NEURODEGENERATIVE DISEASES MEDILABO RFP, INC. (JP) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11583494-B2 Pharmaceutical composition for nasal administration NPC1, CYP3A43, ABCB11 ABCB11 3/4885MAPT 28/4885ABCC4 122/4885
US-11447502-B2 Antibacterial agents: dual-targeted RNA polymerase inhibitors POLM, POLR2E, POLR2H ABCB11 1452/4885MAPT 3318/4885ABCC4 3222/4885
US-20220125782-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR NEURODEGENERATIVE DISEASES HTT, SIRT1, NRDC ABCB11 385/4885MAPT 6/4885ABCC4 553/4885
US-20220298203-A1 THERAPEUTIC AGENTS AND METHODS NR1H4, NR3C1, NR3C2 ABCB11 715/4885MAPT 4807/4885ABCC4 3201/4885
US-20260102392-A1 PROPHYLACTIC OR THERAPEUTIC DRUG FOR NEURODEGENERATIVE DISEASES MAPT, SNCA, FUS ABCB11 488/4885MAPT 1/4885ABCC4 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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