Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.83 |
| ▸ | GAA | P10253 | 3/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.83 |
| ▸ | ABCC3 | O15438 | 3/20 | 0.83 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.83 |
| ▸ | ABCC2 | Q92887 | 3/20 | 0.83 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.83 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.83 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.83 |
| ▸ | SLCO1A2 | P46721 | 2/20 | 0.83 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.83 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23510705 | 1.00 | MAPT (0.83) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL29559659 | 0.95 | ABCB11 (0.83) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL23594215 | 0.95 | ABCB11 (0.83) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL23541658 | 0.95 | ABCB11 (0.83) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL29625757 | 0.94 | MAPT (0.80) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL29625771 | 0.94 | ABCB11 (0.80) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL30988931 | 0.94 | MAPT (0.81) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL14356353 | 0.93 | ABCB11 (0.80) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL13302850 | 0.93 | ABCB11 (0.80) | MAPTABCB11GAAMAPK1ABCC3 | |
| SCHEMBL30063061 | 0.93 | ABCB11 (0.80) | MAPTABCB11GAAMAPK1ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382945-A1 | THERAPEUTIC AGENTS AND METHODS | POP TEST ONCOLOGY LLC (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382945-A1 | THERAPEUTIC AGENTS AND METHODS | POP TEST ONCOLOGY LLC (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702443-B2 | Therapeutic agents and methods | POP TEST ONCOLOGY LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702443-B2 | Therapeutic agents and methods | POP TEST ONCOLOGY LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-11224599-B2 | Therapeutic agents and methods | POP TEST ONCOLOGY LLC | 2022-01-18 | — | — | US | disclosed |
| US-11040037-B2 | Therapeutic agents and methods | POP TEST ONCOLOGY LLC | 2021-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702443-B2 | Therapeutic agents and methods | NR1H4, NR3C1, NR3C2 | MAPT 4807/4885ABCB11 715/4885GAA 2422/4885 |
| US-20230382945-A1 | THERAPEUTIC AGENTS AND METHODS | NR1H4, NR3C1, NR3C2 | MAPT 4807/4885ABCB11 715/4885GAA 2422/4885 |
| US-11224599-B2 | Therapeutic agents and methods | NR1H4, NR3C1, NR3C2 | MAPT 4807/4885ABCB11 715/4885GAA 2422/4885 |
| US-11040037-B2 | Therapeutic agents and methods | NR1H4, NR3C1, NR3C2 | MAPT 4807/4885ABCB11 715/4885GAA 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.