SCHEMBL14356451

SCHEMBL14356451

CC(C)(C)[Si](C)(C)OCCn1c2ccc(CO)cc2c2cc(CO)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.41
DUT P33316 2/20 0.35
KDM4E B2RXH2 4/20 0.35
HPGD P15428 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
MAPT P10636 3/20 0.33
GRM2 Q14416 3/20 0.33
PARP1 P09874 1/20 0.33
PARP2 Q9UGN5 1/20 0.33
POLB P06746 2/20 0.33
PTGER4 P35408 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
RPS6KA5 O75582 1/20 0.32
USP14 P54578 1/20 0.32
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14356453 0.91 PGR (0.34) PGRDUTKDM4EHPGDALDH1A1
SCHEMBL1472722 0.85 PGR (0.47) PGRHPGDALDH1A1MAPTPARP1
SCHEMBL14356452 0.80 DUT (0.34) DUTKDM4EHPGDALDH1A1HSD17B10
SCHEMBL12421883 0.75 DUT (0.34) DUTHSD17B10MAPTRPS6KA5
SCHEMBL12380478 0.74 RAB9A (0.38) DUTMAPTPOLBMEN1KMT2A
SCHEMBL26059803 0.70 DUT (0.35) DUT
SCHEMBL5163862 0.69 KDM4E (0.64) PGRKDM4EHPGDALDH1A1HSD17B10
SCHEMBL662532 0.69 DUT (0.40) DUTALDH1A1MEN1KMT2APPARG
SCHEMBL6577446 0.69 RECQL (0.38) DUTKDM4ETSHRLMNA
SCHEMBL2881359 0.69 CYP4F2 (0.35) DUTPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297297-B2 Organic dye molecules and nonlinear optical polymeric compounds containing chromophores ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2007-11-20 US disclosed
US-7276188-B2 Organic dye molecules and nonlinear optical polymeric compounds containing chromophores ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2007-10-02 US disclosed