Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDH1 | P40925 | 6/20 | 0.37 |
| ▸ | MDH2 | P40926 | 6/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357625 | 0.87 | ADORA3 (0.48) | ADORA3SMN1; SMN2KMT2APOLBNPC1 | |
| SCHEMBL15095778 | 0.85 | ADORA3 (0.56) | ADORA3KMT2APOLBNPC1RAB9A | |
| SCHEMBL12021704 | 0.82 | MAPT (0.47) | ADORA3SMN1; SMN2CYP3A4KMT2APOLB | |
| SCHEMBL17298988 | 0.81 | ADORA3 (0.52) | ADORA3SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL14357630 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP3A4KMT2APOLBNPC1 | |
| SCHEMBL10907042 | 0.81 | ADORA3 (0.52) | ADORA3SMN1; SMN2CYP3A4KMT2APOLB | |
| SCHEMBL7620007 | 0.81 | CYP3A4 (0.56) | SMN1; SMN2CYP3A4KMT2APOLBMEN1 | |
| SCHEMBL19194913 | 0.80 | KMT2A (0.51) | ADORA3CYP3A4KMT2APOLBNPC1 | |
| SCHEMBL14357634 | 0.80 | LMNA (0.57) | ADORA3KMT2APOLBNPC1RAB9A | |
| SCHEMBL12867433 | 0.80 | MAPT (0.45) | ADORA3CYP3A4KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297456-B2 | Photoconductors containing crosslinked polycarbonate polymers | XEROX CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |
| US-7229732-B2 | Imaging members with crosslinked polycarbonate in charge transport layer | XEROX CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |