Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447566 | 1.00 | MEN1 (0.38) | MEN1KMT2AALDH1A1RAB9AHSD11B1 | |
| SCHEMBL29997473 | 0.84 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12266171 | 0.80 | ACHE (0.44) | MEN1KMT2AALDH1A1HSD11B1GRM5 | |
| SCHEMBL2397980 | 0.80 | ACHE (0.44) | MEN1KMT2AALDH1A1HSD11B1GRM5 | |
| SCHEMBL20015582 | 0.76 | GRM5 (0.43) | MEN1KMT2AALDH1A1GRM5GRM1 | |
| SCHEMBL21369533 | 0.76 | ESR2 (0.43) | MEN1KMT2AALDH1A1GRM5GRM1 | |
| SCHEMBL5341385 | 0.76 | ESR2 (0.43) | MEN1KMT2AALDH1A1GRM5GRM1 | |
| SCHEMBL20015306 | 0.76 | GRM5 (0.43) | MEN1KMT2AALDH1A1GRM5GRM1 | |
| SCHEMBL5341383 | 0.76 | ESR2 (0.43) | MEN1KMT2AALDH1A1GRM5GRM1 | |
| SCHEMBL1030522 | 0.75 | ACHE (0.46) | MEN1KMT2AHSD11B1GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254911-A1 | Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-01 | — | — | US | disclosed |
| US-20070254911-A1 | Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254911-A1 | Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators | CNR1, CNR2, GPR18 | MEN1 3547/4885KMT2A 3133/4885ALDH1A1 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.