SCHEMBL14358262

SCHEMBL14358262

CNC=CN1C(=O)C=CC1=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
GMNN O75496 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
THPO P40225 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28572221 0.76 MGLL (0.42) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL22916701 0.73 GMNN (0.30) MGLLGMNNALDH1A1LMNAMAPT
SCHEMBL16377382 0.67 MGLL (0.35) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL28408985 0.67 MGLL (0.39) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL4859515 0.67 MGLL (0.42) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL10544878 0.67 MGLL (0.42) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL9777831 0.66
SCHEMBL1356452 0.65 MGLL (0.33) MGLLGSK3AGSK3B
SCHEMBL9407360 0.64 MGLL (0.42) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL2876847 0.62 MGLL (0.32) MGLLGSK3AGSK3BGMNNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867190-B1 CYTOTOXIN COMPLEXES COMPRISING DIPEPTIDES KYOWA HAKKO KOGYO KK (JP) 2007-12-26 EP disclosed