SCHEMBL28408985

SCHEMBL28408985

O=C1C=CC(=O)N1C=CBr

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.39
FAAH O00519 7/20 0.39
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GMNN O75496 1/20 0.36
THPO P40225 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
GSK3A P49840 2/20 0.35
GSK3B P49841 2/20 0.35
HSP90AA1 P07900 1/20 0.35
TLR9 Q9NR96 1/20 0.35
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28572221 0.82 MGLL (0.42) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL8884966 0.75
SCHEMBL16377382 0.72 MGLL (0.35) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL1356452 0.70 MGLL (0.33) MGLLFAAHGSK3AGSK3B
SCHEMBL9407360 0.69 MGLL (0.42) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL14358262 0.67 MGLL (0.36) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL4859515 0.67 MGLL (0.42) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL2876847 0.67 MGLL (0.32) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL10544878 0.67 MGLL (0.42) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL15301139 0.65 ALDH1A1 (0.32) ALDH1A1LMNAMAPTNPSR1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269519-A Polymethacrylate composition and optical element and display device formed by same 奇美实业股份有限公司 2020-06-12 CN disclosed