Glutarate

Glutarate

SCHEMBL143588

NCCN.O=C(O)CCCC(=O)O.O=C(O)CCCC(=O)O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glutarate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.77
TSHR P16473 3/20 0.77
THRB P10828 2/20 0.77
BLM P54132 2/20 0.77
KMT2A Q03164 2/20 0.77
NPSR1 Q6W5P4 2/20 0.77
GABRR1 P24046 2/20 0.77
GABRR3 A8MPY1 1/20 0.77
GABRP O00591 1/20 0.77
GABRD O14764 1/20 0.77
HDAC3 O15379 1/20 0.77
GABBR2 O75899 1/20 0.77
CYP1A2 P05177 1/20 0.77
GABRA1 P14867 1/20 0.77
GABRB1 P18505 1/20 0.77
GABRG2 P18507 1/20 0.77
GABRB3 P28472 1/20 0.77
GABRR2 P28476 1/20 0.77
SLC6A1 P30531 1/20 0.77
GABRA5 P31644 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL2449984 1.00 LMNA (0.77) LMNATSHRTHRBBLMKMT2A
Glutarate SCHEMBL6815061 0.97 LMNA (0.72) LMNATSHRTHRBBLMKMT2A
Glutarate SCHEMBL28335483 0.97 LMNA (0.72) LMNATSHRTHRBBLMKMT2A
Adipic Acid SCHEMBL11328398 0.93 NFKB1 (0.82) LMNATSHRTHRBBLMKMT2A
Adipic Acid SCHEMBL9133305 0.93 NFKB1 (0.82) LMNATSHRTHRBBLMKMT2A
Adipic Acid SCHEMBL1647321 0.93 NFKB1 (0.82) LMNATSHRTHRBBLMKMT2A
Glutarate SCHEMBL9453439 0.90 LMNA (0.82) LMNATSHRTHRBBLMKMT2A
Glutarate SCHEMBL2915734 0.90 LMNA (0.82) LMNATSHRTHRBBLMKMT2A
Azelaic Acid SCHEMBL11141213 0.90 LMNA (0.83) LMNATSHRTHRBBLMKMT2A
Octanedioate SCHEMBL11875945 0.90 LMNA (0.83) LMNATSHRTHRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129309-A1 COLOR CHANGING FALLOUT REMOVER COMPOSITION AND USES THEREOF ILLINOIS TOOL WORKS INC. (US) 2025-04-24 US claimed
EP-4166637-B1 VEHICLE HARD SURFACE COMPOSITION CONTAINING GRAPHENE ILLINOIS TOOL WORKS (US) 2025-03-26 EP claimed
US-20230257683-A1 VEHICLE HARD SURFACE COMPOSITION CONTAINING GRAPHENE ILLINOIS TOOL WORKS INC. (US) 2023-08-17 US claimed
EP-4166637-A1 VEHICLE HARD SURFACE COMPOSITION CONTAINING GRAPHENE Illinois Tool Works, Inc. (US) 2023-04-19 EP claimed
EP-3506762-A1 IMPROVED PRE-EMERGENT HERBICIDE W. Neudorff GmbH KG (DE) 2019-07-10 EP claimed
WO-2018041916-A1 IMPROVED PRE-EMERGENT HERBICIDE W. NEUDORFF GMBH KG (DE) 2018-03-08 WO claimed
US-20180049958-A1 AGENT FOR IMPROVED OXIDATIVE LIGHTENING OF KERATINIC FIBRES HENKEL AG & CO. KGAA (DE) 2018-02-22 US claimed
US-9663409-B2 Liquid phosphite fertilizer THE ANDERSONS INC. (US) 2017-05-30 US claimed
EP-2579722-B1 SELECTIVE HERBICIDES WITH ACTIVATOR ADJUVANTS NEUDORFF W GMBH KG (DE) 2016-11-23 EP claimed
US-20160331664-A1 AGENTS FOR GENTLY OXIDATIVELY LIGHTENING KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2016-11-17 US claimed
EP-0938290-A1 SHAMPOO COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-09-01 EP claimed
US-5755992-A MIXED WITH POLYMERIC DYE TRANSFER INHIBITOR; ANTISOILANT PRETREATMENT WASH THE PROCTER & GAMBLE COMPANY (US) 1998-05-26 US claimed
EP-0836469-A1 BACTERICIDAL COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1998-04-22 EP claimed
WO-1998004237-A1 SHAMPOO COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-02-05 WO claimed
WO-1998004775-A1 USE OF COMPLEXING AGENTS FOR CELLULOSE AND WOOD BLEACHING, PAPER PRODUCTION AND USED PAPER DEINKING BASF AKTIENGESELLSCHAFT (DE) 1998-02-05 WO claimed
EP-0783034-A2 Chelating agent and detergent comprising the same NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1997-07-09 EP claimed
WO-1997002010-A1 BACTERICIDAL COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1997-01-23 WO claimed
US-5545352-A NONIONIC SURFACTANT, XYLENE OR CUMENE SULFONATES AS HYDROTROPES, WATER OR ORGANIC SOLVENT, A CHELANT COMPONENT, AN ACRYLIC ACID OR ITS SALT AS POLYMER THE PROCTER & GAMBLE COMPANY (US) 1996-08-13 US claimed
WO-1995029220-A1 DETERGENT COMPOSITIONS CONTAINING DIAMINE TETRACARBOXYLIC ACID OR SALTS THEREOF THE PROCTER & GAMBLE COMPANY (US) 1995-11-02 WO claimed
EP-0672749-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1995-09-20 EP claimed