Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484544 | 0.85 | KDM4E (0.38) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL25024693 | 0.81 | HRH3 (0.40) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7167047 | 0.80 | ALDH1A1 (0.40) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7167022 | 0.80 | TAAR1 (0.40) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7169382 | 0.79 | HTR6 (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7169393 | 0.79 | KDM4E (0.35) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7168520 | 0.78 | TAAR1 (0.39) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL17481983 | 0.78 | KDM4E (0.33) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7167374 | 0.78 | HTR6 (0.40) | — | |
| SCHEMBL7444705 | 0.77 | HRH3 (0.41) | HRH3ALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6572664-B2 | Oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2003-06-03 | — | — | US | claimed |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | claimed |
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | BRETON PHILIPPE (FR) | 2002-01-10 | — | — | US | claimed |
| EP-1129691-A2 | Compositions for dyeing keratinous fibers containing indolizine derivatives and dyeing method using same | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-1844109-B1 | USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS | PROCTER & GAMBLE (US) | 2011-03-30 | — | — | EP | disclosed |
| CN-101107327-B | Use of cationic azacyanine dyes for dyeing keratin fibres | PROCTER & GAMBLE | 2010-09-08 | — | — | CN | disclosed |
| CN-101107327-A | Use of cationic azacyanine dyes for dyeing keratin fibres | PROCTER & GAMBLE (US) | 2008-01-16 | — | — | CN | disclosed |
| EP-1844109-A2 | USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006081246-A2 | USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-03 | — | — | WO | disclosed |
| US-6572664-B2 | Oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2003-06-03 | — | — | US | disclosed |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | disclosed |
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | BRETON PHILIPPE (FR) | 2002-01-10 | — | — | US | disclosed |
| EP-1129691-A2 | Compositions for dyeing keratinous fibers containing indolizine derivatives and dyeing method using same | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | KRT18, INMT, IDO1 | HRH3 2380/4885ALDH1A1 897/4885KDM4E 1225/4885 |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | KRT18, INMT, IDO1 | HRH3 2380/4885ALDH1A1 897/4885KDM4E 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.