Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354118 | 0.84 | TSHR (1.00) | TSHRTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL7609036 | 0.78 | TSHR (0.51) | TSHRTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL7646415 | 0.77 | HSD11B1 (0.54) | TSHRTDP1KDM4EALOX5KMT2A | |
| SCHEMBL9508171 | 0.77 | KMT2A (0.61) | TSHRKDM4EHPGDALDH1A1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL31121245 | 0.76 | ALDH1A1 (0.67) | TSHRTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL3279004 | 0.76 | ALOX5 (0.60) | TSHRALDH1A1CA12SMN1; SMN2CA9 | |
| SCHEMBL9760694 | 0.74 | KDM4E (0.56) | TSHRTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL11127626 | 0.72 | ALOX5 (0.56) | TSHRALDH1A1CA12SMN1; SMN2CA9 | |
| SCHEMBL11790045 | 0.72 | TSHR (0.58) | TSHRTDP1KDM4EHPGDALDH1A1 | |
| SCHEMBL27774828 | 0.72 | HPGD (0.54) | TSHRTDP1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | claimed |