SCHEMBL14360703

SCHEMBL14360703

CN(O)C(=O)c1cccc(-n2c(S)nnc2S)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.42
▸ TDP1 Q9NUW8 4/20 0.42
▸ L3MBTL1 Q9Y468 4/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ POLB P06746 2/20 0.42
▸ MAPT P10636 2/20 0.42
▸ USP2 O75604 1/20 0.42
▸ MYC P01106 1/20 0.42
▸ HSPA1A P0DMV8 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ NR4A1 P22736 1/20 0.42
▸ PTPN7 P35236 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ PMM2 O15305 1/20 0.40
▸ MPI P34949 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14093876 0.81 SMN1; SMN2 (0.41) KDM4ETDP1L3MBTL1ALDH1A1MEN1
SCHEMBL13656906 0.76 POLB (0.42) KDM4EMEN1KMT2APOLBGAA
SCHEMBL3279166 0.75 KMT2A (0.53) TDP1L3MBTL1MEN1KMT2AHPGD
SCHEMBL17758889 0.71 PDE4A (0.55) L3MBTL1MAPTHTT
Benzoic Acid SCHEMBL11452692 0.69 TSHR (0.52) KDM4ETDP1L3MBTL1ALDH1A1MEN1
SCHEMBL14093923 0.69 ALDH1A1 (0.50) L3MBTL1ALDH1A1POLBMAPTGAA
SCHEMBL6675237 0.69 HPGD (0.62) TDP1MEN1KMT2APOLBHSD17B10
SCHEMBL14583724 0.69 TDP1 (0.49) KDM4ETDP1L3MBTL1ALDH1A1MAPT
SCHEMBL14344015 0.69 POLB (0.41) KDM4ETDP1L3MBTL1ALDH1A1MEN1
SCHEMBL17758892 0.67 PARP1 (0.55) TDP1L3MBTL1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309564-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-18 — — US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 — — US disclosed
EP-1431813-B1 Photothermographic material with high iodide content and image forming method using same FUJI PHOTO FILM CO LTD (JP) 2007-02-14 — — EP disclosed
EP-1742105-A2 Photothermographic material Fuji Photo Film Co., Ltd. (JP) 2007-01-10 — — EP disclosed
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