SCHEMBL1436087

SCHEMBL1436087

CCCCC(OC(N)=O)C(C)O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.42
CA1 P00915 3/20 0.42
LMNA P02545 4/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
SLC15A1 P46059 1/20 0.37
FAAH O00519 1/20 0.37
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.35
CTSK P43235 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1436142 0.88 LMNA (0.39) CA2CA1LMNACHRM2CHRM4
SCHEMBL28212840 0.86 CA2 (0.44) CA2CA1LMNACHRM2CHRM4
SCHEMBL19025895 0.85 CA2 (0.42) CA2CA1LMNACHRM2CHRM4
SCHEMBL27793523 0.80 CA2 (0.39) CA2CA1LMNACHRM2CHRM4
SCHEMBL11790070 0.80 LMNA (0.39) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL6671730 0.79 LMNA (0.42) CA2CA1LMNACHRM2CHRM4
SCHEMBL223940 0.78 LMNA (0.50) CA2CA1LMNACHRM2CHRM4
SCHEMBL3423347 0.78 CA2 (0.47) CA2CA1LMNACHRM2CHRM4
SCHEMBL1811806 0.77 CA2 (0.42) CA2CA1LMNACHRM2CHRM4
SCHEMBL28637302 0.75 LMNA (0.42) LMNACHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP claimed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP claimed
EP-0675141-A1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-10-04 EP claimed
US-5412049-A Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-05-02 US claimed
CN-112174960-B Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds 吉利德科学公司 2023-10-10 CN disclosed
CN-112174960-A Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds 吉利德科学公司 2021-01-05 CN disclosed
CN-107108615-B Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds 吉利德科学公司 2020-11-20 CN disclosed
EP-1362067-B1 DURABLE REFINISH COATING BASF CORP (US) 2011-03-30 EP disclosed
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP disclosed
EP-1362067-A2 COATING Basf Corporation (US) 2003-11-19 EP disclosed
EP-0915113-B1 High solids thermosetting compositions with dual cure mechanism BASF CORP (US) 2003-05-07 EP disclosed
US-6512069-B1 Carbamate-functional acrylic polymer having an epsilon-caprolactone moiety beta to a carbamate group; useful as clearcoat for automobiles BASF CORPORATION 2003-01-28 US disclosed
US-20030008994-A1 DURABLE REFINISH COATING BASF CORPORATION 2003-01-09 US disclosed
WO-2002050199-A2 COATING BASF CORPORATION, PLEASE SEE GENERAL APPOINTMENT OF REPRESENTATIVE (US) 2002-06-27 WO disclosed
US-5945499-A High solids thermosetting compositions with dual cure mechanism BASF CORPORATION (US) 1999-08-31 US disclosed
US-5907024-A CURABLE COATING SOLUTION CONTAINING A COMPOUND HAVING HYDROXYL AND CARBAMATE FUNCTIONALITY, A POLYISOCYANATE CROSSLINKER AND AN AMINOPLAST CROSSLINKER; COATING THE STEEL PANEL WITH ABOVE SOLUTION AND CURING WITHOUT SAGGING BASF CORPORATION (US) 1999-05-25 US disclosed
EP-0915113-A1 High solids thermosetting compositions with dual cure mechanism BASF CORPORATION (US) 1999-05-12 EP disclosed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP disclosed
EP-0675141-A1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-10-04 EP disclosed
US-5412049-A Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-05-02 US disclosed