SCHEMBL1436142

SCHEMBL1436142

CCCC(OC(N)=O)C(C)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.39
TSHR P16473 5/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ADRA1A P35348 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
AKR1A1 P14550 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1436087 0.88 CA2 (0.42) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL17510954 0.85 LMNA (0.41) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL11790070 0.83 LMNA (0.39) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL6671730 0.83 LMNA (0.42) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL6248027 0.82 TSHR (0.38) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL11752278 0.82 CA1 (0.35) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL28637302 0.78 LMNA (0.42) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL28780670 0.76 LMNA (0.37) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL5357384 0.76 CA1 (0.34) LMNATSHRCHRM1CHRM3CHRM2
SCHEMBL514364 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP claimed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP claimed
EP-0675141-A1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-10-04 EP claimed
US-5412049-A Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-05-02 US claimed
US-4062889-A Preparation of sulfonylureas ERIC LUCIEN 1977-12-13 US claimed
EP-1362067-B1 DURABLE REFINISH COATING BASF CORP (US) 2011-03-30 EP disclosed
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP disclosed
EP-1362067-A2 COATING Basf Corporation (US) 2003-11-19 EP disclosed
EP-0915113-B1 High solids thermosetting compositions with dual cure mechanism BASF CORP (US) 2003-05-07 EP disclosed
US-6512069-B1 Carbamate-functional acrylic polymer having an epsilon-caprolactone moiety beta to a carbamate group; useful as clearcoat for automobiles BASF CORPORATION 2003-01-28 US disclosed
US-20030008994-A1 DURABLE REFINISH COATING BASF CORPORATION 2003-01-09 US disclosed
WO-2002050199-A2 COATING BASF CORPORATION, PLEASE SEE GENERAL APPOINTMENT OF REPRESENTATIVE (US) 2002-06-27 WO disclosed
US-5945499-A High solids thermosetting compositions with dual cure mechanism BASF CORPORATION (US) 1999-08-31 US disclosed
US-5907024-A CURABLE COATING SOLUTION CONTAINING A COMPOUND HAVING HYDROXYL AND CARBAMATE FUNCTIONALITY, A POLYISOCYANATE CROSSLINKER AND AN AMINOPLAST CROSSLINKER; COATING THE STEEL PANEL WITH ABOVE SOLUTION AND CURING WITHOUT SAGGING BASF CORPORATION (US) 1999-05-25 US disclosed
EP-0915113-A1 High solids thermosetting compositions with dual cure mechanism BASF CORPORATION (US) 1999-05-12 EP disclosed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP disclosed
EP-0675141-A1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-10-04 EP disclosed
US-5412049-A Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-05-02 US disclosed