Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874315 | 0.98 | IDO1 (0.50) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL29800442 | 0.98 | IDO1 (0.50) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL221981 | 0.78 | ALDH1A1 (0.51) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL492446 | 0.78 | PSMB8 (0.53) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL30938811 | 0.78 | PSMB8 (0.53) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL719079 | 0.78 | IDO1 (0.50) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL3096380 | 0.78 | IDO1 (0.50) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL5092877 | 0.78 | IDO1 (0.50) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL27890456 | 0.73 | NPC1 (0.47) | IDO1ALDH1A1HSD17B10ADRA2AFBP1 | |
| SCHEMBL27892930 | 0.72 | RAB9A (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278243-B2 | Laser imaging | DATALASE LTD. (GB) | 2012-10-02 | — | — | US | disclosed |
| EP-1704057-B1 | LASER IMAGING | DATALASE LTD (GB) | 2011-03-30 | — | — | EP | disclosed |
| US-20100075848-A1 | Laser Imaging | DATALASE LTD. (GB) | 2010-03-25 | — | — | US | disclosed |
| EP-1704057-A1 | LASER IMAGING | Sherwood Technology LTD. (GB) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005068207-A1 | LASER IMAGING | DATALASE LTD. (GB) | 2005-07-28 | — | — | WO | disclosed |