SCHEMBL14361982

SCHEMBL14361982

CC(C)(COC(=O)C(Br)(Br)Br)COC(=O)C(Br)(Br)Br

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.47
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13660319 0.85 LMNA (0.39) SERPINE1MAPK1HIF1ALMNAHSD17B10
SCHEMBL10179034 0.85 SERPINE1 (0.42) SERPINE1LMNAHSD17B10DGAT1
SCHEMBL5445288 0.79 PRKCA (0.43) SERPINE1LMNAHSD17B10DGAT1
SCHEMBL16860592 0.79 MAPK1 (0.32) MAPK1HIF1A
SCHEMBL1463974 0.75 SERPINE1 (0.38) SERPINE1LMNAHSD17B10DGAT1
SCHEMBL2386487 0.75 SERPINE1 (0.35) SERPINE1DGAT1
SCHEMBL297524 0.74
SCHEMBL12403723 0.73 CYP4F2 (0.38) SERPINE1MAPK1HIF1A
SCHEMBL14040480 0.72 LMNA (0.31) LMNAHSD17B10
SCHEMBL14362038 0.72 MAPK1 (0.37) SERPINE1MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070254246-A1 Developer used for planographic printing plate material and processing method by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-11-01 US disclosed
US-20070254246-A1 Developer used for planographic printing plate material and processing method by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-11-01 US disclosed