Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386487 | 0.89 | SERPINE1 (0.35) | SERPINE1DGAT1 | |
| SCHEMBL14361982 | 0.85 | SERPINE1 (0.47) | SERPINE1LMNAHSD17B10DGAT1 | |
| SCHEMBL1597489 | 0.85 | MAPK1 (0.39) | SERPINE1POLBGAANPSR1LMNA | |
| SCHEMBL9897503 | 0.85 | LMNA (0.39) | SERPINE1POLBGAANPSR1LMNA | |
| SCHEMBL13667252 | 0.83 | SERPINE1 (0.33) | SERPINE1 | |
| SCHEMBL21732963 | 0.82 | SERPINE1 (0.31) | SERPINE1 | |
| SCHEMBL15431806 | 0.81 | LMNA (0.32) | POLBGAANPSR1LMNAHSD17B10 | |
| SCHEMBL18018641 | 0.81 | HTT (0.32) | POLBGAANPSR1 | |
| SCHEMBL13109163 | 0.79 | LMNA (0.35) | LMNAHSD17B10 | |
| SCHEMBL16360730 | 0.79 | MAPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819531-B2 | Multifunctional zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230277616-A9 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. | 2023-09-07 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| WO-2007039416-A1 | FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277616-A9 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | PHOSPHO1, MSN, ZW10 | SERPINE1 4370/4885POLB 1123/4885GAA 1525/4885 |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | SERPINE1 975/4885POLB 569/4885GAA 204/4885 |
| US-11819531-B2 | Multifunctional zwitterionic polymer conjugates | PHOSPHO1, MSN, ZW10 | SERPINE1 4370/4885POLB 1123/4885GAA 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.