Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363777 | 0.86 | MAPT (0.51) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL14363774 | 0.86 | MAPKAPK2 (0.50) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL14363779 | 0.85 | KIF11 (0.46) | ALDH1A1SIRT1 | |
| SCHEMBL14363771 | 0.84 | MAPKAPK2 (0.51) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL14364159 | 0.81 | CHRNA7 (0.55) | SLC6A4ADRA1ACYP1A2CYP2D6HSD17B10 | |
| SCHEMBL21648505 | 0.77 | MAPKAPK2 (0.46) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL21648537 | 0.77 | MAPKAPK2 (0.46) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL21648540 | 0.77 | MAPKAPK2 (0.46) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL14363920 | 0.76 | MAPKAPK2 (0.54) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 | |
| SCHEMBL30363250 | 0.75 | MAPKAPK2 (0.56) | MAPTALDH1A1HTR2BMAPKAPK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147819-A1 | 3H,11H-OXAZOLO[3',4':1,2]PYRIDO[3,4-B]INDOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2007-12-27 | — | — | WO | disclosed |