Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363777 | 0.94 | MAPT (0.51) | MAPKAPK2MAPTTP53SIRT1ABCG2 | |
| SCHEMBL14363773 | 0.88 | ABCG2 (0.52) | MAPTTP53ABCG2ABCB1ADRA1A | |
| SCHEMBL14363770 | 0.84 | MAPT (0.54) | MAPKAPK2MAPTTP53SIRT1ALDH1A1 | |
| SCHEMBL14364155 | 0.84 | ADRA1D (0.50) | MAPTABCG2DRD2DRD1DRD5 | |
| SCHEMBL14363774 | 0.81 | MAPKAPK2 (0.50) | MAPKAPK2MAPTTP53SIRT1ALDH1A1 | |
| SCHEMBL21648537 | 0.72 | MAPKAPK2 (0.46) | MAPKAPK2MAPTTP53SIRT1ABCG2 | |
| SCHEMBL21648505 | 0.72 | MAPKAPK2 (0.46) | MAPKAPK2MAPTTP53SIRT1ABCG2 | |
| SCHEMBL21648540 | 0.72 | MAPKAPK2 (0.46) | MAPKAPK2MAPTTP53SIRT1ABCG2 | |
| SCHEMBL14363920 | 0.72 | MAPKAPK2 (0.54) | MAPKAPK2MAPTTP53SIRT1ABCG2 | |
| SCHEMBL765058 | 0.72 | HTR7 (0.72) | MAPKAPK2MAPTALDH1A1HTR2BMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147819-A1 | 3H,11H-OXAZOLO[3',4':1,2]PYRIDO[3,4-B]INDOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2007-12-27 | — | — | WO | disclosed |