Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180069 | 0.85 | CCR2 (0.64) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL5493789 | 0.84 | CCR2 (0.63) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL5493777 | 0.83 | CCR2 (0.65) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL5495180 | 0.82 | NPC1 (0.64) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL6180924 | 0.80 | KMT2A (0.65) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL5493371 | 0.79 | KMT2A (0.64) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL5780599 | 0.78 | RAB9A (0.75) | CCR2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL5493367 | 0.78 | MAOB (0.59) | CCR2NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL5455627 | 0.77 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5489348 | 0.76 | CCR2 (0.69) | CCR2NPC1RAB9AMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297696-B2 | Antagonists of MCP-1 function and methods of use thereof | TELIK, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297696-B2 | Antagonists of MCP-1 function and methods of use thereof | TELIK, INC. (US) | 2007-11-20 | — | — | US | disclosed |