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SCHEMBL14366165

SCHEMBL14366165

COCCOC(=O)CCCC(=O)N[C@@H](CC(=O)NC(CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1C(=O)N[C@@H](C(C)O)C(=O)NCC(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@H](CC(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N2CCCC2C(=O)N[C@@H](C(N)=O)CSSC1(C)C)C(=O)CNC(CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1C(=O)N[C@@H](C(C)O)C(=O)NCC(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)N(C)CC(=O)N(C)[C@H](CC(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N2CCCC2C(=O)N[C@@H](C(N)=O)CSSC1(C)C

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FCGRT P55899 4/20 0.80
▸ EPHA2 P29317 11/20 0.47
▸ ACE P12821 2/20 0.44
▸ ACE2 Q9BYF1 2/20 0.44
▸ MC4R P32245 1/20 0.43
▸ MC3R P41968 1/20 0.43
▸ MC1R Q01726 1/20 0.43
▸ KEAP1 Q14145 1/20 0.42
▸ NFE2L2 Q16236 1/20 0.42
▸ CHRNA7 P36544 1/20 0.41
▸ CHRNA10 Q9GZZ6 1/20 0.41
▸ CHRNA9 Q9UGM1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12305037 0.89 FCGRT (0.81) FCGRTEPHA2ACEACE2MC4R
SCHEMBL10132153 0.88 FCGRT (0.64) FCGRTEPHA2ACEACE2KEAP1
SCHEMBL12253738 0.86 FCGRT (0.66) FCGRTEPHA2ACEACE2KEAP1
SCHEMBL12766288 0.86 FCGRT (0.66) FCGRTEPHA2ACEACE2KEAP1
SCHEMBL12253644 0.77 FCGRT (0.62) FCGRTEPHA2ACEACE2MC4R
SCHEMBL24625820 0.65 KLK7 (0.53) EPHA2ACEACE2
SCHEMBL24625791 0.64 EPHA2 (0.51) FCGRTEPHA2ACEACE2
SCHEMBL26880160 0.64 F11 (0.57) MC4RMC3RMC1R
SCHEMBL26902265 0.63 F11 (0.57) MC4RMC3RMC1R
SCHEMBL24625831 0.63 SSTR2 (0.56) FCGRTEPHA2ACEACE2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn BIOGEN HEMOPHILIA INC. 2007-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn FCGRT, FCGR3B, FCGR1A FCGRT 1/4885EPHA2 920/4885ACE 1806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.