Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
| ▸ | CPN1 | P15169 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893075 | 0.83 | EPHX2 (0.67) | EPHX2EPHX1 | |
| SCHEMBL5361247 | 0.82 | EPHX2 (0.50) | EPHX2EPHX1CA1CA2CA12 | |
| SCHEMBL18559935 | 0.82 | EPHX2 (0.50) | EPHX2EPHX1CA1CA2CA12 | |
| SCHEMBL7895774 | 0.80 | EPHX2 (0.49) | EPHX2EPHX1CA1CA2CA12 | |
| SCHEMBL25934453 | 0.77 | EPHX2 (0.50) | EPHX2EPHX1CA1CA2CA12 | |
| SCHEMBL18997474 | 0.77 | ALDH1A1 (0.51) | EPHX2EPHX1CA1CA2CA12 | |
| SCHEMBL18560182 | 0.77 | EPHX2 (0.51) | EPHX2EPHX1ALDH1A1DPP4DPP8 | |
| SCHEMBL14344886 | 0.77 | CPN1 (0.40) | EPHX2EPHX1CPN1CPB2ALDH1A1 | |
| SCHEMBL18091012 | 0.77 | ATM (0.45) | EPHX2EPHX1CA1CA2CA12 | |
| SCHEMBL508551 | 0.77 | ATM (0.45) | EPHX2EPHX1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |