Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.64 |
| ▸ | ANPEP | P15144 | 4/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PEPD | P12955 | 2/20 | 0.35 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049482 | 1.00 | MMP2 (0.64) | MMP2ANPEPBRD4MMP1MMP3 | |
| SCHEMBL15079079 | 1.00 | MMP2 (0.64) | MMP2ANPEPBRD4MMP1MMP3 | |
| SCHEMBL17679758 | 1.00 | MMP2 (0.64) | MMP2ANPEPBRD4MMP1MMP3 | |
| SCHEMBL15079077 | 1.00 | MMP2 (0.64) | MMP2ANPEPBRD4MMP1MMP3 | |
| Hydrochloric Acid SCHEMBL29414150 | 0.98 | MMP2 (0.62) | MMP2ANPEPBRD4MMP1MMP3 | |
| Hydrochloric Acid SCHEMBL30337475 | 0.98 | MMP2 (0.62) | MMP2ANPEPBRD4MMP1MMP3 | |
| Hydrochloric Acid SCHEMBL29129130 | 0.98 | MMP2 (0.62) | MMP2ANPEPBRD4MMP1MMP3 | |
| SCHEMBL13865290 | 0.83 | ANPEP (0.49) | MMP2ANPEPBRD4ALDH1A1GABRR1 | |
| SCHEMBL18536557 | 0.81 | ANPEP (0.51) | MMP2ANPEPALDH1A1CYP3A4MAPT | |
| SCHEMBL14288714 | 0.80 | MMP2 (0.42) | MMP2ANPEPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300929-B2 | Mediators of hedgehog signaling pathways, compositions and uses related thereto | CURIS, INC. (US) | 2007-11-27 | — | — | US | disclosed |