Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367104 | 0.83 | MMP2 (0.64) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| SCHEMBL8049482 | 0.83 | MMP2 (0.64) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| SCHEMBL15079079 | 0.83 | MMP2 (0.64) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| SCHEMBL17679758 | 0.83 | MMP2 (0.64) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| SCHEMBL15079077 | 0.83 | MMP2 (0.64) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| Hydrochloric Acid SCHEMBL29414150 | 0.81 | MMP2 (0.62) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| Hydrochloric Acid SCHEMBL30337475 | 0.81 | MMP2 (0.62) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| Hydrochloric Acid SCHEMBL29129130 | 0.81 | MMP2 (0.62) | ANPEPMMP2BRD4ALDH1A1GABRR1 | |
| SCHEMBL13865291 | 0.79 | MMP2 (0.39) | ANPEPMMP2BRD4ALDH1A1CYP1A2 | |
| SCHEMBL10794700 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | AAAS, AMPD2, AMPD3 | ANPEP 63/4885MMP2 2536/4885BRD4 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.