Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392193 | 0.84 | — | — | |
| SCHEMBL2820598 | 0.80 | EPHX2 (0.45) | HRH4LTA4HTSHRCHRM2CHRM1 | |
| SCHEMBL17760478 | 0.80 | CHRM2 (0.41) | LTA4HTSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL38662837 | 0.80 | CNR1 (0.39) | LTA4HTSHRMAPTCHRM2CHRM1 | |
| SCHEMBL30779509 | 0.79 | PDE8B (0.39) | LTA4HMAPT | |
| SCHEMBL8562910 | 0.79 | POLB (0.44) | HRH4LTA4HTSHRMAPTCHRM2 | |
| SCHEMBL16982095 | 0.76 | LTA4H (0.43) | HRH4LTA4HTSHRMAPTALOX15 | |
| SCHEMBL28165548 | 0.76 | CHRM2 (0.53) | HRH4HRH3TSHRCHRM2CHRM1 | |
| SCHEMBL4773996 | 0.74 | GPR119 (0.51) | CYP3A4 | |
| SCHEMBL30779612 | 0.74 | SIGMAR1 (0.41) | LTA4HMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |