Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14522636 | 1.00 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL14367276 | 0.86 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL14522639 | 0.86 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL5116695 | 0.86 | KIF11 (0.51) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL5561425 | 0.81 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL4102537 | 0.81 | MAPT (0.45) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL5118303 | 0.80 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL5489353 | 0.79 | ALDH1A1 (0.45) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL5120055 | 0.78 | KIF11 (0.39) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL14367275 | 0.78 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254870-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-11-01 | — | — | US | disclosed |
| US-20070254870-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254870-A1 | Compounds, compositions and methods | ALPP, PCNA, MKI67 | PDE4A 3029/4885PDE4B 3016/4885PDE4C 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.