Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 10/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367867 | 1.00 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL13672067 | 0.84 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BL3MBTL1CA2 | |
| SCHEMBL31129268 | 0.81 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL6974656 | 0.80 | ADRA1A (0.47) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL1021052 | 0.80 | ADRA1A (0.47) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL14367866 | 0.79 | POLB (0.53) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL14367881 | 0.79 | POLB (0.53) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL6174128 | 0.79 | POLB (0.53) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL27374312 | 0.78 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 | |
| SCHEMBL5844958 | 0.77 | LMNA (0.46) | ADRA1DADRA1AADRA1BL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |