Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 4/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368990 | 0.84 | CCR3 (0.44) | CCR3 | |
| SCHEMBL4553193 | 0.84 | CCR3 (0.44) | CCR3 | |
| SCHEMBL14368732 | 0.83 | HPGDS (0.58) | HPGDSALDH1A1 | |
| SCHEMBL14368706 | 0.81 | ACKR3 (0.47) | ACKR3HPGDS | |
| SCHEMBL4426712 | 0.81 | ACKR3 (0.47) | ACKR3HPGDS | |
| SCHEMBL27757345 | 0.80 | SSTR3 (0.55) | CCR3 | |
| SCHEMBL14368669 | 0.80 | SSTR3 (0.55) | CCR3 | |
| SCHEMBL14368773 | 0.80 | HPGDS (0.41) | HPGDSCNR1ALDH1A1CCR3 | |
| SCHEMBL14368747 | 0.79 | HRH3 (0.48) | CNR1ALDH1A1 | |
| SCHEMBL27778266 | 0.79 | HRH3 (0.48) | CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | OPRL1, OPRM1, SIGMAR1 | ACKR3 278/4885HPGDS 732/4885HCRTR1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.