Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290641 | 0.93 | CYP2D6 (0.35) | LMNAHTTSMN1; SMN2HSD11B1CYP2D6 | |
| SCHEMBL1716790 | 0.90 | LMNA (0.37) | LMNAHTTSMN1; SMN2RECQLHSD11B1 | |
| SCHEMBL1712432 | 0.88 | KDM4E (0.40) | LMNAHTTSMN1; SMN2RECQLHSD11B1 | |
| Sulfuric Acid SCHEMBL1491998 | 0.88 | LMNA (0.36) | LMNAHTTSMN1; SMN2RECQLHSD11B1 | |
| Sulfuric Acid SCHEMBL2182781 | 0.86 | CYP2C19 (0.35) | LMNASMN1; SMN2CYP2D6MAPK1KMT2A | |
| Sulfuric Acid SCHEMBL291858 | 0.86 | CYP2D6 (0.35) | LMNACYP2D6MAPK1KMT2AKDM4E | |
| SCHEMBL146684 | 0.86 | LMNA (0.38) | LMNAHTTSMN1; SMN2RECQLHSD11B1 | |
| SCHEMBL1034142 | 0.85 | CYP2D6 (0.49) | LMNAHTTSMN1; SMN2RECQLHSD11B1 | |
| SCHEMBL141770 | 0.84 | C5AR1 (0.38) | LMNAHTTSMN1; SMN2RECQLHSD11B1 | |
| SCHEMBL1723901 | 0.83 | CYP2D6 (0.40) | LMNASMN1; SMN2CYP2D6KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263642-B1 | Colouring bleaches | HENKEL AG & CO KGAA (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-9693937-B2 | Foil applicator | HENKEL AG & CO. KGAA (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20150174019-A1 | FOIL APPLICATOR | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | US | disclosed |
| EP-2427247-B1 | FOIL APPLICATOR | HENKEL AG & CO KGAA (DE) | 2013-12-18 | — | — | EP | disclosed |
| EP-2427247-A2 | FOIL APPLICATOR | Henkel AG & Co. KGaA (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-20120055500-A1 | Foil Applicator | HENKEL AG & CO. KGAA (DE) | 2012-03-08 | — | — | US | disclosed |
| EP-2320854-B1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-8034122-B2 | Bleaching agent comprising 2-acylpyridinium derivatives | HENKEL AG & CO. KGAA (DE) | 2011-10-11 | — | — | US | disclosed |
| EP-2344113-A2 | MEANS FOR TREATING KERATIN FIBRES CONTAINING CATIONIC PYRIDINIUM DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2011-07-20 | — | — | EP | disclosed |
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | US | disclosed |
| EP-2320854-A2 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-2263642-A2 | Colouring bleaches | Henkel AG & Co. KGaA (DE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2010127902-A2 | FOIL APPLICATOR | HENKEL AG & CO. KGAA (DE) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010054981-A2 | COMBINATION OF CATIONIC BLEACH ACTIVATORS AND DYES | HENKEL AG & CO. KGAA (DE) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010029006-A2 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | KRT18, CBR3, ACOX3 | LMNA 631/4885HTT 1600/4885SMN1; SMN2 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.