SCHEMBL14368939

SCHEMBL14368939

C=CCOCC1CCCN(C[C@@H]2CCCC[C@H]2NC(=O)CCc2ccc(Cl)cc2)C1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CCR3 P51677 19/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14392523 1.00 CCR3 (0.45) CCR3
SCHEMBL4434871 0.89 CCR3 (0.47) CCR3
SCHEMBL14369069 0.89 CCR3 (0.47) CCR3
SCHEMBL14392669 0.86 CCR3 (0.43) CCR3
SCHEMBL14368942 0.86 CCR3 (0.43) CCR3
SCHEMBL14392354 0.84 CCR3 (0.44) CCR3
SCHEMBL5664557 0.83 CCR3 (0.50) CCR3
SCHEMBL5664554 0.83 CCR3 (0.50) CCR3
SCHEMBL14369063 0.83 CCR3 (0.48) CCR3
SCHEMBL27778278 0.81 CCR3 (0.47) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070259888-A1 Novel Compounds ASTRAZENECA AB (SE) 2007-11-08 — — US disclosed
US-20070259888-A1 Novel Compounds ASTRAZENECA AB (SE) 2007-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259888-A1 Novel Compounds OPRL1, OPRM1, SIGMAR1 CCR3 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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