Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 14/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426694 | 1.00 | HTT (0.43) | HTTCCR3DRD3DRD2HTR2A | |
| SCHEMBL14369049 | 0.89 | CCR3 (0.44) | HTTCCR3DRD2HTR2AHTR2C | |
| SCHEMBL5664036 | 0.89 | CCR3 (0.44) | CCR3DRD2HTR2ACYP2D6SLC6A2 | |
| SCHEMBL4428998 | 0.89 | CCR3 (0.44) | CCR3DRD2HTR2ACYP2D6SLC6A2 | |
| SCHEMBL4428996 | 0.89 | CCR3 (0.44) | CCR3DRD2HTR2ACYP2D6SLC6A2 | |
| SCHEMBL14368995 | 0.89 | CCR3 (0.40) | CCR3CYP2D6 | |
| SCHEMBL14368994 | 0.88 | CCR3 (0.43) | HTTCCR3DRD3DRD2HTR2A | |
| SCHEMBL4426204 | 0.88 | CCR3 (0.43) | HTTCCR3DRD3DRD2HTR2A | |
| SCHEMBL4566657 | 0.87 | CCR3 (0.44) | HTTCCR3DRD2HTR2AHTR2C | |
| SCHEMBL14369059 | 0.87 | CCR3 (0.44) | HTTCCR3DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | OPRL1, OPRM1, SIGMAR1 | HTT 2970/4885CCR3 247/4885DRD3 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.