Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27530934 | 0.99 | MMP1 (0.56) | MMP1MMP3MMP9MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL5966853 | 0.99 | MMP1 (0.56) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL31293473 | 0.90 | MMP1 (0.55) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL15223643 | 0.88 | ALDH1A1 (0.64) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL29484050 | 0.87 | MMP1 (0.55) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL29973208 | 0.87 | MMP1 (0.53) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL11786518 | 0.87 | MMP1 (0.53) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL24346312 | 0.86 | ALDH1A1 (0.72) | POLBALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL5493329 | 0.86 | ALDH1A1 (0.72) | POLBALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL27336415 | 0.86 | ALDH1A1 (0.72) | POLBALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4685150-A1 | METHOD FOR PRODUCING AMIDE GROUP-CONTAINING COMPOUND USING N-CARBOXYAMINO ACID ANHYDRIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024225377-A1 | METHOD FOR PRODUCING AMIDE GROUP-CONTAINING COMPOUND USING N-CARBOXYAMINO ACID ANHYDRIDE | 中外製薬株式会社 | 2024-10-31 | — | — | WO | disclosed |
| US-20220017940-A1 | FLUORESCENT PROBE FOR DETECTING CARBOXYPEPTIDASE ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2022-01-20 | — | — | US | disclosed |
| US-20110053892-A1 | Imidazo[4,5-d]Pyridazine Compounds For Treating Viral Infections | LEIVERS MARTIN | 2011-03-03 | — | — | US | disclosed |
| WO-2011026024-A2 | IMIDAZO [4,5-D] PYRIDAZINE COMPOUNDS FOR TREATING VIRAL INFECTIONS | GLAXOSMITHKLINE LLC (US) | 2011-03-03 | — | — | WO | disclosed |
| US-20110052534-A1 | Imidazopyridazine Compounds for Treating Viral Infections | LEIVERS MARTIN | 2011-03-03 | — | — | US | disclosed |
| WO-2011026091-A1 | IMIDAZOPYRIDAZINE COMPOUNDS FOR TREATING VIRAL INFECTIONS | GLAXOSMITHKLINE LLC (US) | 2011-03-03 | — | — | WO | disclosed |
| US-7507764-B2 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes | TEGO BIOSCIENCES CORPORATION (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060223761-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-05 | — | — | US | disclosed |
| US-20050143327-A1 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes | LUNA LABS USA, LLC | 2005-06-30 | — | — | US | disclosed |
| US-20030229024-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | AUDIA JAMES E (US) | 2003-12-11 | — | — | US | disclosed |
| US-6476263-B1 | Compounds for inhibiting β-amyloid peptide release and/or its synthesis | ELAN PHARMACEUTICALS, INC. | 2002-11-05 | — | — | US | disclosed |
| US-20020052322-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | ELAN PHARMACEUTICALS, INC. | 2002-05-02 | — | — | US | disclosed |
| US-6211235-B1 | ALZHEIMERS DISEASE | ELAN PHARMACEUTICALS, INC. | 2001-04-03 | — | — | US | disclosed |
| US-6207710-B1 | FOR THERAPY OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. | 2001-03-27 | — | — | US | disclosed |
| US-6191166-B1 | ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | disclosed |
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | disclosed |
| EP-0364804-A1 | Non-peptide renin inhibitors | ABBOTT LABORATORIES (US) | 1990-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052322-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | MMP1 1115/4885MMP3 632/4885MMP9 535/4885 |
| US-20110052534-A1 | Imidazopyridazine Compounds for Treating Viral Infections | ACE, ACE2, TPMT | MMP1 1595/4885MMP3 2945/4885MMP9 3849/4885 |
| US-20060223761-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | MMP1 1277/4885MMP3 706/4885MMP9 572/4885 |
| US-20030229024-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | MMP1 1115/4885MMP3 632/4885MMP9 535/4885 |
| US-20110053892-A1 | Imidazo[4,5-d]Pyridazine Compounds For Treating Viral Infections | MAVS, ZC3HAV1, IL5 | MMP1 1974/4885MMP3 3431/4885MMP9 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.