Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375022 | 1.00 | LMNA (0.48) | LMNAFAAHTGM2BCHEACHE | |
| SCHEMBL14197113 | 0.90 | LMNA (0.48) | LMNAFAAHTGM2BCHEACHE | |
| SCHEMBL4879327 | 0.90 | LMNA (0.48) | LMNAFAAHTGM2BCHEACHE | |
| SCHEMBL14197151 | 0.88 | LMNA (0.54) | LMNAFAAHTGM2BCHEACHE | |
| SCHEMBL4884973 | 0.88 | LMNA (0.54) | LMNAFAAHTGM2BCHEACHE | |
| SCHEMBL5369903 | 0.77 | MGLL (0.49) | MAOBALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL14370633 | 0.77 | MGLL (0.49) | MAOBALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL31043796 | 0.76 | LMNA (0.47) | LMNAFAAHTGM2ALDH1A1NPC1 | |
| SCHEMBL11813314 | 0.76 | TP53 (0.68) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1223807 | 0.76 | RAB9A (0.67) | LMNAACHEMAOBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279494-B2 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | PFIZER INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279494-B2 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | PFIZER INC. (US) | 2007-10-09 | — | — | US | disclosed |